Harris leads the team with 691 rushing yards on 137 tries and two touchdowns.
He had injured his back 14 in the fourth quarter of a week Los Angeles Rams, but was ultimately classified as healthy earlier this week and was not on the injury report on Wednesday when the Patriots held their initial practice to prepare for the dolphins.
However, Harris was put on the injury report for his ankle the next day and opened the door to the former No. 1 back Sony Michel to rise back to the top.
Patriots who ran back coach Ivan Fears said on Dec. 11 that Michel would be ready if the opportunity presented itself.
“He’s a real team player. He knows Damien plays really well and Sony is waiting for the opportunity to show what he can do,” Fears said at the time. “He always trains hard and is the guy you like and can rely on. I’m very happy. No matter who goes down, I know I have great players who can step in and keep us updated . “
The Patriots (6-7) are sticking to the playoffs hopes, and ESPN’s Football Power Index gives them a 3% chance of qualifying.
The Patriots also excluded top kickoff returnees Donte Moncrief (Thighs) for Sunday’s game.