City ranks have been hit by a COVID-19 outbreak that forced the club’s training base to temporarily close.
They hit Chelsea 3-1 at Stamford Bridge on Sunday without Ederson, Kyle Walker, Ferran Torres and Gabriel Jesus and Guardiola says he has a limited number to choose from ahead of Wednesday’s Old Trafford derby.
“We don’t have a lot of players and as I said after the first press conference it’s okay to play a game or two but if this goes on for a long time and I can only use 14 or 15 players it will be more difficult.” said Guardiola.
“Like everyone in the world, we adapt, you have to adapt our lives and professions as much as possible, and we have no alternative.
“The most important thing is that people can have a good rest with COVID and the guys are good with it and try to avoid it as much as possible.”
City face a United States team tied with the Premier League leaders Liverpool After a string of unbeaten home games dating back to November 1, City returned to the race for the title with an impressive win at Stamford Bridge, and Guardiola believes United will be one of the main contenders for the trophy.
Ole Gunnar Solskjaer says Manchester United are confident ahead of Manchester City semi-finals.
“You have always been a contender,” he said.
“Every year when we start the season United is a competitor. If it hasn’t happened in the past few seasons, it’s a question for them.
“Years ago it was between two, maybe three, but not more. Now there are a lot of teams and everyone can win and everyone can lose.
“We will now see the consistency of every club and the ups and downs, every club has good and bad moments.
“As long as the competition goes on, I think the big teams will lose fewer points. This is the real Premier League competition where anyone can beat anyone.”
“It’s about being calm, being fresh for the moment of the game, not getting infected by this pandemic situation around the world and being fresh the moment the game starts.”